Lorre's third show was Dharma & Greg, which was premiered one year before the end of Cybill in 1997.The show starred Jenna Elfman and Thomas Gibson as the title characters, whose characters were complete opposites: Dharma's world view being more spiritual, 'free spirit' type instilled by "hippie" parents, contrasted with Greg's world view of structure, social status requirements, and "white collar duty" instilled by his generations of affluent parents/ancestors.During his two years at college he "majored in rock 'n' roll and pot and minored in LSD." He also admits to drinking in his past, telling EW, "I led a dissolute youth until 47." He now is in recovery.
The show aired for four seasons on CBS and received critical acclaim, winning a Primetime Emmy Award in 1995 for Outstanding Supporting Actress in a Comedy Series for co-star Christine Baranski.
The show also won two Golden Globe Awards in 1996 for Best Television Series - Musical or Comedy and Best Actress in a Television Series - Musical or Comedy for Cybill Shepherd.
She also got the part of Lindsey Kellogg on FOX’s North Shore, in addition to several guest stints. She played Addison on Saw II and Saw IV, as well as on 40 Days and 40 Nights with Josh Hartnett.
She was on Charmed, One Tree Hill, Andromeda, Supernatural, The Outer Limits, and Veronica Mars. She followed it up with a series of independent films, including the thrillers Mind Storm and Ripper, in addition to Suddenly Naked.
Lorre's fourth show was Two and a Half Men with co-creater Lee Aronsohn.
The show focuses on two Harper brothers, Charlie and Alan (Charlie Sheen and Jon Cryer).The show premiered on CBS in 2003 and has become the highest-rated sitcom in America.However, CBS briefly canceled the show up until its eighth season following several incidents of production shutdowns allegedly due to Sheen's serious problems related to drug and alcohol abuse, which culminated in his verbal attacks directed at Lorre during a radio interview. hired Ashton Kutcher as Sheen's replacement, and the show was renewed for its eleventh season.Soon, Emmanuelle Vaugier became known for her recurring role of Detective Jessica Angell on CSI: New York.She worked on another CBS show, Two and a Half Men, and even landed roles on other series like Smallville and Painkiller Jane.Lorre was born as Charles Michael Levine in Bethpage, Long Island, New York, to a Jewish family.